❖ CASE 3

An 8-year-old girl is brought in by her mother for evaluation of allergies. Each
year in the spring the child develops a runny nose; itchy, watery eyes; and
sneezing. She has been treated in the past with diphenhydramine, but the
child’s teacher says that she is very drowsy during school. She has no other
medical problems and is on no chronic medications. Her examination is unremarkable
today. You diagnose her with seasonal allergic rhinitis and prescribe
fexofenadine.

◆ What is the mechanism of action of antihistamine medications?
◆ What are the common side effects of antihistamine medications?
◆ What is the pharmacologic basis of switching to fexofenadine?

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referance : Case Files™ Pharmacology