Antibiotics

The Antibiotic Tree

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Penicillin

❖ CASE 4

A 22-year-old woman is diagnosed with a generalized anxiety disorder.
Which of the following is a contraindication for the use of a benzodiazepine
to treat this patient?

A. Cigarette smoking
B. Seizure disorder
C. Diabetes mellitus
D. Sleep apnea

Aspirin Side Effects

❖ CASE 3

An 8-year-old girl is brought in by her mother for evaluation of allergies. Each
year in the spring the child develops a runny nose; itchy, watery eyes; and
sneezing. She has been treated in the past with diphenhydramine, but the
child’s teacher says that she is very drowsy during school. She has no other
medical problems and is on no chronic medications. Her examination is unremarkable
today. You diagnose her with seasonal allergic rhinitis and prescribe
fexofenadine.

◆ What is the mechanism of action of antihistamine medications?
◆ What are the common side effects of antihistamine medications?
◆ What is the pharmacologic basis of switching to fexofenadine?

Write your answers to Comment section .

referance : Case Files™ Pharmacology

❖ CASE 2

A 40-year-old woman presents for evaluation of her chronic migraine

headaches. She reports that approximately once a month she has a severe, unilateral

headache associated with nausea and extreme photophobia. The

headache will last for a full day if not treated. She has had success in reducing

the severity of the headaches with opioid pain medications, but usually she is

too nauseous to take them. When she is able to tolerate them, she will have to

sleep for several hours afterwards. She is missing about a day of work a month

because of the headaches. She has no other significant medical history and

takes no medications on a regular basis. Her examination today is normal. You

decide to prescribe sumatriptan for her to try with her next migraine headache.

◆ Which receptor is the site of action of sumatriptan?
◆ What is the mechanism of action of sumatriptan?

Write your answers to Comment section .

referance : Case Files™ Pharmacology